As the Cannabis market expands for medical and recreational use, so does the need for standardized quality control in the industry. When it comes to Cannabis quality control there are lots of things to consider, from moisture content to pesticide use.
Moisture Content – Cannabis flower moisture content needs to be tested and controlled to: minimize the chance of mold formation; control microbiological levels; ensure proper drying, curing and storage conditions; and support product shelf life. Some manufacturing processes for marijuana quality assurance plan also need a certain water content inside the starting material.
Terpenoids and Cannabinoids Analysis
The degree of terpenoids and cannabinoids within the starting material determines the most appropriate industrial processing method and which final cannabis product is going to be manufactured. This analysis is usually completed using LC-MS (Liquid Chromatography Mass Spectrometry) or GC (Gas Chromatography). LC-MS and GC require a flow of inert gas such as hydrogen or nitrogen, each of which can be simply supplied via a gas generator. Uncover more about the Peak Scientific selection of gas generators for GC & LC-MS here.
Pesticides and Herbicides – Similar to other agricultural crops and products designed for human consumption, Cannabis plants should be tested for herbicides and pesticides. Detecting pesticides and herbicides can be difficult as a result of complexity of cannabis material. GCMS (Gas Chromatography Mass Spectrometry) is normally used for this purpose.
Microbiological Screening – Medical Cannabis is often employed for HIV and cancer patients in which the patient’s defense mechanisms has become compromised. Therefore, high microbial levels or pathogenic micro-organisms might be life-threatening. It is important then that several Mycotoxins and fungus types ought to be detected included in cannabis quality control and release specifications.
Residual Solvents – Where solvents happen to be used included in Cannabis product processing, solvent residuals in the final products needs to be tested to ensure they satisfy the accepted criteria. The FDA has published zvqtob criteria for residual solvents in APIs for pharmaceutical use.
Heavy Metals – Like a number of other plants, Cannabis draws metals from your earth. It really is therfore required to test for Mercury, Lead, Arsen and Cadmium.
Cannabinoid Concentration – Concentration ranges for cannabinoids like THC,THCa, CBD, CBDa, CBN, CBC, CBG should match the ranges specified on the product label, based upon product usage purpose, patient’s condition, age etc. Cannabinoid concentrations could be tested using LC-MS (Liquid Chromatography Mass Spectrometry) and HPLC (High End Liquid Chromatography) . You can find a wide range of Peak Scientific nitrogen gas generators designed especially for LC-MS, available here.
Terpene Concentration – Terpenes increase cannabinoids’ therapeutic effects and are recognized to have their own health and fitness benefits, in addition they bring about Cannabis taste and aroma. They can be detected using GC.
Taking the above into account, it is actually clear that there exists a necessity for standarized procedures for all the Cannabis analysis and testing process to be able to guarantee safe use. The safest way to supply cannabis testing laboratories with gas for his or her LC-MS and GC is by gas generators, which do not present the health and safety risks associated with gas cylinders.